cis-4-(Tosyl­oxymeth­yl)cyclo­hexa­ne­carboxylic acid

Solubility of Cis, Cis-Muconic Acid in Various Polar Solvents from 298.15 K to 348.15 K

The present work concerns with an investigation on the solubility of cis,cis-muconic acid dissolution in different polar solvents by characterizing and modeling the dissolution as a function of temperature. Water, ethanol, 2-propanol and acetic acid have been investigated as solvents in the range temperatures from a 298.15 to 348.15 K. Owing to the absence of cis,cis-muconic acid solubility...

trans-4-(Tosyl­oxymeth­yl)cyclo­hexane­carboxylic acid

The title compound, C(15)H(20)O(5)S, is an inter-mediate in the synthesis of a new type of poly(amido-amine) (PAMAM) dendrimer. The cyclo-hexane ring exhibits a chair conformation, with C-C bond lengths in the range 1.518 (3)-1.531 (3) Å and C-C-C angles in the range 110.45 (19)-112.09 (19)°; these agree well with the values in other cyclo-hexane derivatives described in the literature. In the ...

Computational study of three dimensional potential energy surfaces in intermolecular hydrogen bonding of cis-urocanic acid

trans-4-Nitro­phenyl 4-(tosyl­oxymeth­yl)cyclo­hexa­necarboxyl­ate

The title compound, C(21)H(23)NO(7)S, is an important inter-mediate in the synthesis of poly(amido-amine) dendrimers. The cyclo-hexane ring adopts a chair conformation. The dihedral angle between the two aromatic rings is 69.5 (2)°. The mol-ecules are linked into a zigzag chain along the b axis by C-H⋯O hydrogen bonds.

9-cis-Retinoic Acid and 1,25-dihydroxy Vitamin D3 Improve the Differentiation of Neural Stem Cells into Oligodendrocytes through the Inhibition of the Notch and Wnt Signaling Pathways

Background: Differentiating oligodendrocyte precursor cells (OPCs) into oligodendrocytes could be improved by inhibiting signaling pathways such as Wnt and Notch. 9-cis-retinoic acid (9-cis-RA) and 1,25-dihydroxyvitamin D3 (1,25[OH]2D3) can ameliorate oligodendrogenesis. We investigated whether they could increase oligodendrogenesis by inhibiting the Wnt and Notch signaling pathways.Methods: Co...